Diseases title

Acanthosis nigricans - Insulin resistance - muscle cramps - acral enlargement )

Chrom mut
Orpha Number: 90301

This syndrome is characterised by the association of acanthosis nigricans, insulin resistance, severe muscle cramps and acral hypertrophy. At least five cases have been described in the literature so far. Enlargement of the kidneys was also reported in some cases. Transmission is autosomal recessive.
source: Orphanet